Activated through the antibiotic rifampicin and many plant metabolites, like hyperforin, guggulipid, colupulone, and isoflavones. Response to certain ligands is species-distinct. Activated by Obviously developing steroids, for example pregnenolone and progesterone. Binds to some response aspect while in the promoters of your CYP3A4 and ABCB1/MDR1 g